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Important Safety Information

Who should not take Neulasta®?

Do not take Neulasta® if you have had a serious allergic reaction to pegfilgrastim (Neulasta®) or to filgrastim (Neupogen®).

What should I tell my health care provider before taking Neulasta®? Tell your healthcare provider if you:

  • Have sickle cell trait or sickle cell disease
  • Have had severe skin reactions to acrylic adhesives
  • Are allergic to latex
  • Have any other medical problems
  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are possible serious side effects of Neulasta®?

  • Spleen Rupture. Your spleen may become enlarged and can rupture while taking Neulasta. A ruptured spleen can cause death. Call your doctor right away if you have pain in the left upper stomach area or left shoulder tip area. This pain could mean your spleen is enlarged or ruptured.
  • A serious lung problem called acute respiratory distress syndrome (ARDS). Call your health care provider or get emergency medical help right away if you get any of these symptoms of ARDS: fever, shortness of breath, trouble breathing, or a fast rate of breathing.
  • Serious Allergic Reactions. Get emergency medical help right away if you get any of these symptoms of a serious allergic reaction with Neulasta: shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, sweating, and hives. If you have an allergic reaction during the delivery of Neulasta, remove the On-body Injector for Neulasta by grabbing the edge of the adhesive pad and peeling off the On-body Injector for Neulasta. Get emergency medical help right away.
  • Sickle Cell Crises. Severe sickle cell crises, and sometimes death, can happen in people with sickle cell trait or disease who receive filgrastim, a medicine similar to Neulasta.

The most common side effect of Neulasta is pain in the bones and in your arms and legs.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Neulasta. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For more information about Neulasta, talk with your healthcare provider or pharmacist; go to, or call 1-844-696-3852 (1-844-MYNEULASTA).

Please see the Neulasta Patient Information for additional information.


Neulasta® (pegfilgrastim) is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

It is not known if Neulasta is safe and effective in children.

Caring for Someone During

If you are helping to care for a friend or family member who is fighting cancer with chemotherapy, the support you provide is important. Whether reminding them about appointments, tracking their chemotherapy side effects, or helping with daily tasks, your support can make a difference.

Ways to help someone during chemotherapy

Here are a few thoughtful ways you can help someone during chemotherapy:

  • Provide transportation to and from doctor appointments
  • Run errands such as shopping for groceries or taking children to or from school
  • Stock their refrigerator with easily heated meals in disposable containers
  • Help with household chores such as vacuuming, laundry, dishes, making beds
  • Create a “travel bag” for them that is large enough to take items to and from their chemo appointments, with items to help them pass the time (books, magazines), to help keep them comfortable (blanket, small pillow, cozy socks), to help keep them warm (hat, scarf), and help with possible side effects of treatment (hard candies and water bottle for dry mouth or metallic taste and tissues for tears or runny nose)
  • Show them you care—visit them, call them, send them a card, write them a note

Learn about a serious side effect of strong chemotherapy

If you are a caregiver for a patient with cancer receiving strong chemotherapy, continue to explore this website. This website provides information about a serious side effect of strong chemotherapy, which can increase the risk of infection. You can also learn how Neulasta® can help people undergoing strong chemotherapy boost white blood cell counts to a level high enough to help reduce the risk of infection. You may also want to learn about other patients who helped reduce their risk of infection with Neulasta® during chemotherapy. Then explore the helpful resources for cancer patients and caregivers for additional information and support.


Help to limit your out-of-pocket cost of Neulasta® based on eligibility


Reach out for information and support during chemotherapy