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Important Safety Information

Who should not take Neulasta®?

Do not take Neulasta® if you have had a serious allergic reaction to pegfilgrastim (Neulasta®) or to filgrastim (Neupogen®).

What should I tell my health care provider before taking Neulasta®? Tell your healthcare provider if you:

  • Have sickle cell trait or sickle cell disease
  • Have had severe skin reactions to acrylic adhesives
  • Are allergic to latex
  • Have any other medical problems
  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are possible serious side effects of Neulasta®?

  • Spleen Rupture. Your spleen may become enlarged and can rupture while taking Neulasta. A ruptured spleen can cause death. Call your doctor right away if you have pain in the left upper stomach area or left shoulder tip area. This pain could mean your spleen is enlarged or ruptured.
  • A serious lung problem called acute respiratory distress syndrome (ARDS). Call your health care provider or get emergency medical help right away if you get any of these symptoms of ARDS: fever, shortness of breath, trouble breathing, or a fast rate of breathing.
  • Serious Allergic Reactions. Get emergency medical help right away if you get any of these symptoms of a serious allergic reaction with Neulasta: shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, sweating, and hives. If you have an allergic reaction during the delivery of Neulasta, remove the On-body Injector for Neulasta by grabbing the edge of the adhesive pad and peeling off the On-body Injector for Neulasta. Get emergency medical help right away.
  • Sickle Cell Crises. Severe sickle cell crises, and sometimes death, can happen in people with sickle cell trait or disease who receive filgrastim, a medicine similar to Neulasta.

The most common side effect of Neulasta is pain in the bones and in your arms and legs.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Neulasta. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For more information about Neulasta, talk with your healthcare provider or pharmacist; go to, or call 1-844-696-3852 (1-844-MYNEULASTA).

Please see the Neulasta Patient Information for additional information.


Neulasta® (pegfilgrastim) is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

It is not known if Neulasta is safe and effective in children.

Helpful Resources

Explore these tools, resources, and organizations for information and support during chemotherapy.


Neulasta® Product Information Sheet

Read about how Neulasta® helps reduce the risk of infection during strong chemotherapy. Download and print the Neulasta® Product Information Sheet, which will be available in multiple languages.

The product information provided in this site is intended only for residents of the United States.

Helpful links during chemotherapy treatment

You are not alone in your fight against cancer. In addition to your healthcare team, family, and friends, you can reach out to the organizations listed below for information and support during chemotherapy.

These third party resources are for your information only. Amgen does not endorse and is not responsible for the content included in these resources.

When using any of these resources, look over the information you receive carefully, so that you can understand how it may apply to your specific support needs. Always consult your doctor if you have specific questions or experience any chemotherapy side effects.

American Cancer Society® (ACS)

News, information, and support.

Phone (toll-free): 800-227-2345

Cancer Hope Network

National, nonprofit organization offering free and confidential one-on-one emotional support to adult cancer patients and their families.

Phone (toll-free): 1-877-467-3638

Cancer Support Community®

Support, education and research for people living with cancer.

Phone: 202-659-9709 or toll-free 888-793-9355

National Cancer Institute (NCI)

The NCI, established under the National Cancer Institute Act of 1937, is the Federal Government's principal agency for cancer research and training.

Phone (toll-free): 800-4-CANCER (800-422-6237)

National Comprehensive Cancer Network® (NCCN®)

Alliance of leading cancer centers that offers patient friendly resources, including disease-specific treatment guidelines.

Phone: 215-690-0300

Patient Advocate Foundation (PAF)

Direct Case management, education and financial support for people living with chronic and debilitating diseases.

Phone: 757-873-6668 or toll-free 800-532-5274

Prevent Cancer Foundation (PCF)

Nonprofit dedicated to savings lives through cancer prevention and early detection.

Phone (toll-free): 800-227-2732


Help to limit your out-of-pocket cost of Neulasta® based on eligibility


Real patients with cancer share their stories