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Important Safety Information

Who should not take Neulasta®?

Do not take Neulasta® if you have had a serious allergic reaction to pegfilgrastim (Neulasta®) or to filgrastim (Neupogen®).

What should I tell my health care provider before taking Neulasta®? Tell your healthcare provider if you:

  • Have sickle cell trait or sickle cell disease
  • Have had severe skin reactions to acrylic adhesives
  • Are allergic to latex
  • Have any other medical problems
  • Are pregnant or plan to become pregnant
  • Are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are possible serious side effects of Neulasta®?

  • Spleen Rupture. Your spleen may become enlarged and can rupture while taking Neulasta. A ruptured spleen can cause death. Call your doctor right away if you have pain in the left upper stomach area or left shoulder tip area. This pain could mean your spleen is enlarged or ruptured.
  • A serious lung problem called acute respiratory distress syndrome (ARDS). Call your health care provider or get emergency medical help right away if you get any of these symptoms of ARDS: fever, shortness of breath, trouble breathing, or a fast rate of breathing.
  • Serious Allergic Reactions. Get emergency medical help right away if you get any of these symptoms of a serious allergic reaction with Neulasta: shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, sweating, and hives. If you have an allergic reaction during the delivery of Neulasta, remove the On-body Injector for Neulasta by grabbing the edge of the adhesive pad and peeling off the On-body Injector for Neulasta. Get emergency medical help right away.
  • Sickle Cell Crises. Severe sickle cell crises, and sometimes death, can happen in people with sickle cell trait or disease who receive filgrastim, a medicine similar to Neulasta.

The most common side effect of Neulasta is pain in the bones and in your arms and legs.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Neulasta. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For more information about Neulasta, talk with your healthcare provider or pharmacist; go to, or call 1-844-696-3852 (1-844-MYNEULASTA).

Please see the Neulasta Patient Information for additional information.


Neulasta® (pegfilgrastim) is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

It is not known if Neulasta is safe and effective in children.

Taking Neulasta®

How Neulasta® is given

Neulasta® is given as a shot under the skin (called a subcutaneous injection). There are two ways in which you may receive your Neulasta. Your healthcare provider will choose with you which one is appropriate.

On-body Injector for Neulasta®

The On‑body Injector for Neulasta® is a small, lightweight, injection system applied on the same day you have chemotherapy. It is designed to deliver your dose of Neulasta® approximately 27 hours after it has been activated and applied by your doctor.1-3

Please see the Neulasta® Patient Prescribing Information and the On‑body Injector for Neulasta® Patient Instructions For Use for complete instructions and information about the On‑body Injector
for Neulasta®.

Neulasta® Shot

You should only receive a dose of Neulasta® on the day your healthcare provider tells you. You should not receive your dose of Neulasta® any sooner than 24 hours after you finish receiving your chemotherapy.1

If you are giving someone else Neulasta® injections, it is important that you know how to inject Neulasta®. Please see the Patient Prescribing Information to read How To Prepare and Give a Neulasta® Injection (see page 2).

On-body Injector for Neulasta® Sharps Container Disposal Program

The injector must be properly disposed after use to avoid accidental needle stick.1,3 To participate in the On-body Injector for Neulasta® Sharps container disposal program, please call
1-844-MYNEULASTA (1-844-696-3852) or download and complete this form and mail to:

PO Box 68376
Indianapolis IN 46209-6872


Help to limit your out-of-pocket cost of Neulasta® based on eligibility



Reach out for information and support during chemotherapy


  1. Neulasta® (pegfilgrastim) Prescribing Information, Amgen.
  2. Neulasta® (pegfilgrastim) Patient Product Information, Amgen.
  3. Neulasta® (pegfilgrastim) Patient Instructions For Use, Amgen.