Indication

Neulasta® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of
cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

Neulasta® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

Neulasta® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

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With Neulasta® Onpro®, you can help fight
the risk of infection from home.*


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Enjoy the Comforts of Home

With Neulasta® Onpro®, you can spend the day after strong chemo at home or other appropriate setting. Relaxing on the couch. If you feel up to it, taking a walk. Enjoying your family. The innovative delivery system is designed to automatically deliver Neulasta® the next day–so you don't have to go back to the doctor.

How Neulasta® Onpro® Works

Right after your strong chemo treatment, your healthcare provider will apply the On-body Injector to your skin. The On-body Injector is designed to automatically deliver your Neulasta® dose over 45 minutes, approximately 27 hours after application. Once your dose is complete, remove the Injector and dispose of it according to the Patient Instructions for Use.

The summary does not replace the Patient Instructions for Use. If you are using Neulasta® Onpro®, it’s important that you review the Patient Instructions, and call your doctor if you have any questions.

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FAQs about Neulasta® Onpro®

  • What is Neulasta​® Onpro​​®?

    The Neulasta​​® Onpro​​® kit includes a single dose of Neulasta​​® and a single-use On-body Injector.

  • What is the On-body Injector for Neulasta®?

    The On-body Injector is a small, lightweight delivery system applied to the skin during your chemo appointment. It's designed to automatically administer your dose of Neulasta® as an under-the-skin (subcutaneous) injection the next day, so you may not have to return to the doctor just for a Neulasta® injection.

  • How is the On-body Injector for Neulasta® applied?

    Your doctor will use the prefilled syringe with Neulasta® co packaged in the Neulasta® Onpro® kit to fill the On-body Injector prior to applying it. The prefilled syringe with Neulasta® and the On-body Injector are provided to your doctor as part of Neulasta® Onpro® kit. The On-body Injector is applied directly to your skin using a self-adhesive backing. - See more at: https://www.neulasta.com/support/faq/#sthash.8eRG7Wdn.dpuf

  • How does the On-body Injector for Neulasta® work?

    The On-body Injector for Neulasta® is programmed to deliver your dose about 27 hours after your doctor places the device on your skin. The dose of Neulasta® will be delivered over about 45 minutes. During dose delivery and for 1 hour after delivery, it is best to stay in a place where you or a caregiver can monitor the On-body Injector for Neulasta® to make sure you receive your full dose of Neulasta® and watch for symptoms of an allergic reaction.

  • What should I avoid while the On-body Injector for Neulasta® is in place?

    While the On-body Injector for Neulasta® is in place you should avoid:

    • traveling, driving or operating heavy machinery during hour 26 through hour 29 after the On-body Injector for Neulasta® is applied.
    • sleeping on the On-body Injector for Neulasta® or applying pressure on the On-body Injector for Neulasta. The On-body Injector for Neulasta may not work properly.
    • bumping the On-body Injector for Neulasta® or knocking it off your body.
    • getting body lotion, creams, oils, and skin cleansing products near the On-body Injector for Neulasta®. These products may loosen the adhesive that holds the On-body Injector for Neulasta® onto your body.
    • using hot tubs, whirlpools, or saunas, and direct sunlight. These may affect Neulasta®.
    • peeling off or disturbing the On-body Injector for Neulasta® adhesive before you receive your full dose of Neulasta.
  • How should I dispose of the On-body Injector for Neulasta®?

    The On-body Injector for Neulasta® contains batteries, electronics, and a needle. The On-body Injector should be placed in a sharps disposal container, with an appropriate sized opening, regardless of whether or not the needle is exposed. Follow instructions provided by your healthcare provider or by state or local laws. To participate in Amgen’s voluntary disposal program, please call 1-844-MYNEULASTA (1-844-696-3852) or sign up now.

  • Who should I contact if I have additional questions about Neulasta® Onpro®?

    Talk to your doctor for more information on Neulasta®, or call the Amgen Medical Information line at (866) 822-4832.

* If, for any reason, you believe you did not receive your full dose of Neulasta® or that your On-body Injector is not working correctly, immediately contact your healthcare provider.

Important Safety Information

Who should not take Neulasta®?

Do not take Neulasta® if you have had a serious allergic reaction to Neulasta® (pegfilgrastim) or to NEUPOGEN® (filgrastim).

What should I tell my health care provider before taking Neulasta®? Tell your healthcare provider if you:

  • Have sickle cell trait or sickle cell disease
  • Have had severe skin reactions to acrylic adhesives
  • Are allergic to latex
  • Have problems with your kidneys
  • Have any other medical problems
  • Are pregnant or plan to become pregnant. It is not known if Neulasta® may harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if Neulasta® passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are possible serious side effects of Neulasta®?

  • Spleen Rupture. Your spleen may become enlarged and can rupture while taking Neulasta®. A ruptured spleen can cause death. Call your doctor right away if you have pain in the left upper stomach area or left shoulder tip area. This pain could mean your spleen is enlarged or ruptured.
  • A serious lung problem called Acute Respiratory Distress Syndrome (ARDS). Call your healthcare provider or get emergency medical help right away if you get any of these symptoms of ARDS: fever, shortness of breath, trouble breathing, or a fast rate of breathing.
  • Serious Allergic Reactions. Get emergency medical help right away if you get any of these symptoms of a serious allergic reaction with Neulasta®: shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, sweating, and hives.

If you have an allergic reaction during the delivery of Neulasta®, remove the On-body Injector for Neulasta® by grabbing the edge of the adhesive pad and peeling off the On-body Injector. Get emergency medical help right away.

  • Sickle Cell Crises. Severe sickle cell crises, and sometimes death, can happen in people with sickle cell trait or disease who receive filgrastim, a medicine similar to Neulasta®.
  • Kidney injury (glomerulonephritis). Kidney injury has been seen in patients who received Neulasta®. You should notify your healthcare provider right away if you experience puffiness in your face or ankles, blood in your urine or brown colored urine or you notice you urinate less than usual.
  • Increased white blood cell count (leukocytosis). Your doctor will check your blood during treatment with Neulasta ®.
  • Capillary Leak Syndrome. Neulasta® can cause fluid to leak from blood vessels into your body’s tissues. This condition is called "Capillary Leak Syndrome" (CLS). CLS can quickly cause you to have symptoms that may become life-threatening. Get emergency medical help right away if you develop any of the following symptoms:
    • swelling or puffiness and are urinating less often
    • trouble breathing
    • swelling of your stomach area (abdomen) and feeling of fullness
    • dizziness or feeling faint
    • a general feeling of tiredness
    • The most common side effect of Neulasta® is pain in the bones and in your arms and legs.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Neulasta®. Call your doctor for medical advice about side effects. You may report negative side effects to the FDA at 1-800-FDA-1088.

For more information about Neulasta®, talk with your healthcare provider or pharmacist; go to www.neulasta.com, or call 1-844-696-3852 (1-844-MYNEULASTA).

Please see Neulasta® Patient Information.

Important Safety Information
Who should not take Neulasta®?
Do not take Neulasta® if you have had a serious allergic reaction to Neulasta® (pegfilgrastim) or to NEUPOGEN® (filgrastim).
What should I tell my health care provider before taking Neulasta®? Tell your healthcare provider if you:
• Have sickle cell trait or sickle cell disease

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