Indication

Neulasta® is a prescription medicine used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer
(non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low white blood cell count.

Neulasta® is a prescription medicine used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low white blood cell count.

Neulasta® is a prescription medicine used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low white blood cell count.

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Over 450,000 patients have used Neulasta® Onpro® to fight infection risk from home.*


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Get Your Day Back with Neulasta® Onpro®

Today with Neulasta® Onpro®, most patients can spend the day after strong chemo at home-to be with their families, or just to sleep in. Used by over 450,000 patients, only Neulasta® Onpro® is designed to automatically deliver Neulasta® the next day-so you don't have to go back to the doctor.

How Neulasta® Onpro® Works

Right after your strong chemo treatment, your healthcare provider will apply the on-body-injector (OBI) to your skin. The OBI is designed to automatically deliver your Neulasta® dose over 45 minutes, approximately 27 hours after application. Once your dose is complete, remove the Injector and dispose of it according to the Patient Instructions for Use.

The summary does not replace the Patient Instructions for Use. If you are using Neulasta® Onpro®, it’s important that you review the Patient Instructions, and call your doctor if you have any questions.

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FAQs about Neulasta® Onpro®

  • What is Neulasta​® Onpro​​®?

    The Neulasta​​® Onpro​​® kit includes a single dose of Neulasta​​® and a single-use On-body Injector.

  • What is the On-body Injector for Neulasta®?

    The On-body Injector is a small, lightweight delivery system applied to the skin during your chemo appointment. It's designed to automatically administer your dose of Neulasta® as an under-the-skin (subcutaneous) injection the next day, so you may not have to return to the doctor just for a Neulasta® injection.

  • How is the On-body Injector for Neulasta® applied?

    Your doctor will use the prefilled syringe with Neulasta® co packaged in the Neulasta® Onpro® kit to fill the On-body Injector prior to applying it. The prefilled syringe with Neulasta® and the On-body Injector are provided to your doctor as part of Neulasta® Onpro® kit. The On-body Injector is applied directly to your skin using a self-adhesive backing. - See more at: https://www.neulasta.com/support/

  • How does the On-body Injector for Neulasta® work?

    The On-body Injector for Neulasta® is programmed to deliver your dose about 27 hours after your doctor places the device on your skin. The dose of Neulasta® will be delivered over about 45 minutes. During dose delivery and for 1 hour after delivery, it is best to stay in a place where you or a caregiver can monitor the On-body Injector for Neulasta® to make sure you receive your full dose of Neulasta® and watch for symptoms of an allergic reaction.

  • What should I avoid while the On-body Injector for Neulasta® is in place?

    While the On-body Injector for Neulasta® is in place you should avoid:

    • traveling, driving or operating heavy machinery during hour 26 through hour 29 after the On-body Injector for Neulasta® is applied.
    • sleeping on the On-body Injector for Neulasta® or applying pressure on the On-body Injector for Neulasta. The On-body Injector for Neulasta may not work properly.
    • bumping the On-body Injector for Neulasta® or knocking it off your body.
    • getting body lotion, creams, oils, and skin cleansing products near the On-body Injector for Neulasta®. These products may loosen the adhesive that holds the On-body Injector for Neulasta® onto your body.
    • using hot tubs, whirlpools, or saunas, and direct sunlight. These may affect Neulasta®.
    • peeling off or disturbing the On-body Injector for Neulasta® adhesive before you receive your full dose of Neulasta.
  • What's the difference between a biosimilar and Neulasta®?

    Because Neulasta® is a protein made by a living organism, a biosimilar is not identical to Neulasta®

  • How should I dispose of the On-body Injector for Neulasta®?

    The On-body Injector for Neulasta® contains batteries, electronics, and a needle. The On-body Injector should be placed in a sharps disposal container, with an appropriate sized opening, regardless of whether or not the needle is exposed. Follow instructions provided by your healthcare provider or by state or local laws. To participate in Amgen’s voluntary disposal program, please call 1-844-MYNEULASTA (1-844-696-3852) or sign up now.

  • Who should I contact if I have additional questions about Neulasta® Onpro®?

    Talk to your doctor for more information on Neulasta®, or call the Amgen Medical Information line at (866) 822-4832.

* If, for any reason, you believe you did not receive your full dose of Neulasta® or that your On-body Injector is not working correctly, immediately contact your healthcare provider, as an incomplete dose could increase infection risk.

Important Safety Information

Do not take Neulasta® if you have had a serious allergic reaction to pegfilgrastim or filgrastim.

Before you receive Neulasta®, tell your healthcare provider about all of your healthcare conditions, including if you:

  • Have a sickle cell disorder
  • Have had severe skin reactions to acrylic adhesive
  • Are allergic to latex – The needle cap on the prefilled syringe contains dry natural rubber (derived from latex).
  • Have kidney problems
  • Are pregnant or plan to become pregnant. It is not known if Neulasta® may harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if Neulasta® passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible serious side effects of Neulasta®?

  • Spleen Rupture. Your spleen may become enlarged and can rupture while taking Neulasta®. A ruptured spleen can cause death. Call your healthcare provider right away if you have pain in the left upper stomach area or left shoulder tip area.
  • A serious lung problem called Acute Respiratory Distress Syndrome (ARDS). Call your healthcare provider or get emergency medical help right away if you have shortness of breath with or without a fever, trouble breathing, or a fast rate of breathing.
  • Serious Allergic Reactions. Neulasta® can cause serious allergic reactions. These reactions can cause a rash over your whole body, shortness of breath, wheezing, dizziness, swelling around your mouth or eyes, fast heart rate and sweating.

If you have an allergic reaction during the delivery of Neulasta®, remove the on-body-injector for Neulasta® by grabbing the edge of the adhesive pad and peeling off the on-body-injector. Get emergency medical help right away.

  • Sickle Cell Crises. You may have a serious sickle cell crisis, which could lead to death, if you have a sickle cell disorder and receive Neulasta®.
  • Kidney injury (glomerulonephritis). Neulasta® can cause kidney injury. Call your healthcare provider right away if you develop any of the following symptoms: swelling of your face or ankles, blood in your urine or dark colored urine, or you urinate less than usual.
  • Increased white blood cell count (leukocytosis). Your healthcare provider will check your blood during treatment with Neulasta®.
  • Capillary Leak Syndrome. Neulasta® can cause fluid to leak from blood vessels into your body’s tissues. This condition is called "Capillary Leak Syndrome" (CLS). CLS can quickly cause you to have symptoms that may become life-threatening. Get emergency medical help right away if you develop any of the following symptoms:
    • swelling or puffiness and are urinating less than usual
    • trouble breathing
    • swelling of your stomach area (abdomen) and feeling of fullness
    • dizziness or feeling faint
    • a general feeling of tiredness
  • Inflammation of the aorta (aortitis). Inflammation of the aorta (the large blood vessel which transports blood from the heart to the body) has been reported in patients who received Neulasta®. Symptoms may include fever, abdominal pain, feeling tired, and back pain. Call your healthcare provider if you experience these symptoms.

The most common side effect of Neulasta® is pain in your bones and in your arms and legs.

These are not all the possible side effects of Neulasta®. Call your healthcare provider for medical advice about side effects. You may report negative side effects to the FDA at 1-800-FDA-1088.

Please see Neulasta® Patient Information.

Important Safety Information
Do not take take Neulasta® if you have had a serious allergic reaction to pegfilgrastim or filgrastim.
Before you receive Neulasta®, tell your healthcare provider about all of your healthcare conditions, including if you:
• Have a sickle cell disorder
• Have had severe skin reactions to acrylic adhesive

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