Indication

Neulasta® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

Neulasta® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer Read more medicines (chemotherapy) that can cause fever and low blood cell count. Close

Neulasta® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, Read more in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count. Close

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Frequently Asked Questions

If you have questions about Neulasta® or Neulasta® Onpro®, you can call the Neulasta® Support Line toll-free at 1-844-MYNEULASTA (1-844-696-3852) any time for assistance or answers to your questions about Neulasta®. Talk to your doctor if you have any questions or concerns about your health or treatment.

FAQ

FAQs about Neulasta® medicine

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  • What is Neulasta®?

    Neulasta® is a prescription medicine used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

  • Who should receive Neulasta®?

    Neulasta® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count. Talk to your doctor to see if Neulasta® may be appropriate for you.

  • Who should not take Neulasta®?

    Do not take Neulasta® if you have have a serious allergic reaction to Neulasta® (pegfilgrastim) or to NEUPOGEN® (filgrastim). Talk to your doctor to see if Neulasta® may be appropriate for you.

  • What should I tell my health care provider before taking Neulasta®?

    Before you receive Neulasta®, tell your healthcare provider if you:

    • Have sickle cell trait or sickle cell disease
    • Have had severe skin reactions to acrylic adhesives
    • Are allergic to latex
    • Have problems with your kidneys
    • Have any other medical problems
    • Are pregnant or plan to become pregnant. It is not known if Neulasta® may harm your unborn baby.
    • Are breastfeeding or plan to breastfeed. It is not known if Neulasta® passes into your breast milk.

    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • How does strong chemotherapy result in low white blood cell counts?

    While chemotherapy is fighting cancer cells, it can also harm normal cells in the body that divide rapidly. Strong chemotherapy described as myelosuppressive (my-eh-lo-suh-press-iv) can lower the number of infection-fighting white blood cells called neutrophils in your body. White blood cells are a key part of your immune system.

  • What kind of drug is Neulasta®?

    Medications like Neulasta® may be called white blood cell boosters because they help your body produce more infection-fighting white blood cells during strong chemotherapy. These medications are man-made forms of a substance called granulocyte (gran-yoo-loh-site) colony-stimulating factor (G-CSF) that is naturally produced by the body. They stimulate the growth of a type of white blood cell called neutrophils, which are important in the body's fight against infection.

  • How does Neulasta® work?

    Neulasta® works like a natural protein in your body to promote the growth of new white blood cells. Neulasta® helps protect against the risk of infection in a chemotherapy cycle with just one injection. It is a prescription medication given approximately 24 hours after you receive chemotherapy treatment to provide protection through that cycle.

  • What are the study results for Neulasta®?

    In a key study of 928 breast cancer patients who received up to 4 cycles of strong chemotherapy, one group of patients received Neulasta® (the study group), while the other group did not receive Neulasta® (the placebo group). Neulasta® was shown to help protect against the risk of infection with fever (sometimes called febrile neutropenia or neutropenic fever) through strong chemo treatment. The most common side effect experienced with Neulasta® was aching in the bones or muscles.

  • What are the possible serious side effects of Neulasta®?

    The possible serious side effects of Neulasta® include:

    • Spleen Rupture. Your spleen may become enlarged and can rupture while taking Neulasta®. A ruptured spleen can cause death. Call your doctor right away if you have pain in the left upper stomach area or left shoulder tip area. This pain could mean your spleen is enlarged or ruptured.
    • A serious lung problem called Acute Respiratory Distress Syndrome (ARDS). Call your healthcare provider or get emergency medical help right away if you get any of these symptoms of ARDS: fever, shortness of breath, trouble breathing, or a fast rate of breathing.
    • Serious Allergic Reactions. Get emergency medical help right away if you get any of these symptoms of a serious allergic reaction with Neulasta®: shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, sweating, and hives.

    If you have an allergic reaction during the delivery of Neulasta®, remove the On-body Injector for Neulasta® by grabbing the edge of the adhesive pad and peeling off the On-body Injector. Get emergency medical help right away.

    • Sickle Cell Crises. Severe sickle cell crises, and sometimes death, can happen in people with sickle cell trait or disease who receive filgrastim, a medicine similar to Neulasta®.
    • Kidney injury (glomerulonephritis). Kidney injury has been seen in patients who received Neulasta®. You should notify your healthcare provider right away if you experience puffiness in your face or ankles, blood in your urine or brown colored urine or you notice you urinate less than usual.
    • Increased white blood cell count (leukocytosis). Your doctor will check your blood during treatment with Neulasta®.
    • Capillary Leak Syndrome. Neulasta® can cause fluid to leak from blood vessels into your body's tissues. This condition is called "Capillary Leak Syndrome" (CLS). CLS can quickly cause you to have symptoms that may become life-threatening. Get emergency medical help right away if you develop any of the following symptoms:
      • swelling or puffiness and are urinating less often
      • trouble breathing
      • swelling of your stomach-area (abdomen) and feeling of fullness
      • dizziness or feeling faint
      • a general feeling of tiredness

    Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

    These are not all the possible side effects of Neulasta®. For more information, ask your doctor or pharmacist.

  • What are the most common side effects of Neulasta®?

    The most common side effect of Neulasta® is pain in the bones and in your arms and legs.

    Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

    These are not all the possible side effects of Neulasta. For more information, ask your doctor or pharmacist.

  • Do I need to be aware of any drug interactions with Neulasta®?

    No formal drug interaction studies have been conducted. When discussing your treatment options, tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Should I take Neulasta® if I am pregnant or nursing?

    Neulasta® has not been studied in pregnant women, and its effects on unborn babies are not known. If you take Neulasta® while you are pregnant, it is possible that small amounts of it may get into your baby’s blood. It is not known if Neulasta® can get into human breast milk. If you are pregnant, plan to become pregnant, think you may be pregnant, or are breastfeeding, you should tell your doctor before using Neulasta®. If you become pregnant during Neulasta® treatment, you are encouraged to enroll in Amgen's Pregnancy Surveillance Program. You should call 1-800-77-AMGEN (1-800-772-6436) to enroll.

  • What are the ingredients in Neulasta®?

    The active ingredient in Neulasta® is pegfilgrastim. Inactive ingredients in Neulasta® include acetate, sorbitol, polysorbate 20, and sodium in water for injection.

  • Is financial assistance available to help pay for Neulasta®?

    Yes, patients may be eligible for programs that provide financial assistance in connection with Neulasta®. Call 1-844-MYNEULASTA (1-844-696-3852) any time for assistance or answers to your questions about Neulasta®.

    Learn more about financial assistance for Neulasta®.

  • What resources and patient support are available for people taking Neulasta®?

    Amgen, the maker of Neulasta®, provides patients and caregivers with helpful resources and support. You can also call Neulasta® Support Line toll-free at 1-844-MYNEULASTA (1-844-696-3852) any time for assistance or answers to your questions about Neulasta®. Always remember that your doctor is the first person you should turn to if you have particular concerns about your health or treatment.

  • How will I receive Neulasta®?

    Neulasta® is given as an injection under the skin at least 24 hours after you receive chemotherapy treatment to provide protection through that cycle. There are two ways in which you may receive your Neulasta®—either Neulasta® by manual injection or Neulasta® Onpro®. Your healthcare provider will choose with you which one is most appropriate.

  • Do I have to return to the doctor’s office the day after chemotherapy to get my Neulasta® injection?

    Neulasta® is given as an injection under the skin at least 24 hours after you receive chemotherapy treatment to provide protection through that cycle. There are two ways in which you may receive your Neulasta®—either Neulasta® by manual injection or Neulasta® Onpro®. Your healthcare provider will choose with you which one is most appropriate. If you and your doctor decide to use Neulasta® Onpro®, you may not have to return to the doctor the day after chemotherapy just for a Neulasta® injection.

    If, for any reason, you believe you did not receive your full dose of Neulasta® or that your On-body Injector is not working correctly, immediately contact your healthcare provider.

  • Who should I contact if I have additional questions about Neulasta®?

    Talk to your doctor for more information on Neulasta®, or call the Amgen Medical Information line at (866) 822-4832.

FAQs about Neulasta® Onpro®

  • What is Neulasta® Onpro®?

    The Neulasta® Onpro® kit includes a single dose of Neulasta® and a single-use On-body Injector.

  • What is the On-body Injector for Neulasta®?

    The On-body Injector is a small, lightweight delivery system applied to the skin during your chemo appointment. It's designed to automatically administer your dose of Neulasta® as an under-the-skin (subcutaneous) injection the next day, so you may not have to return to the doctor just for a Neulasta® injection.

  • How is the On-body Injector for Neulasta® applied?

    Your doctor will use the prefilled syringe with Neulasta® copackaged in the Neulasta® Onpro® kit to fill the On-body Injector prior to applying it. The prefilled syringe with Neulasta® and the On-body Injector are provided to your doctor as part of Neulasta® Onpro® kit. The On-body Injector is applied directly to your skin using a self-adhesive backing.

  • How does the On-body Injector for Neulasta® work?

    The On-body Injector for Neulasta® is programmed to deliver your dose about 27 hours after your doctor places the device on your skin. The dose of Neulasta® will be delivered over about 45 minutes. During dose delivery and for 1 hour after delivery, it is best to stay in a place where you or a caregiver can monitor the On-body Injector for Neulasta® to make sure you receive your full dose of Neulasta® and watch for symptoms of an allergic reaction.

  • What should I avoid while the On-body Injector for Neulasta® is in place?

    While the On-body Injector for Neulasta® is in place you should avoid:

    • traveling, driving or operating heavy machinery during hour 26 through hour 29 after the On-body Injector for Neulasta® is applied.
    • sleeping on the On-body Injector for Neulasta® or applying pressure on the On-body Injector for Neulasta®. The On-body Injector for Neulasta® may not work properly.
    • bumping the On-body Injector for Neulasta® or knocking it off your body.
    • getting body lotion, creams, oils, and skin cleansing products near the On-body Injector for Neulasta®. These products may loosen the adhesive that holds the On-body Injector for Neulasta® onto your body.
    • using hot tubs, whirlpools, or saunas, and direct sunlight. These may affect Neulasta®.
    • peeling off or disturbing the On-body Injector for Neulasta® adhesive before you receive your full dose of Neulasta.
  • How should I dispose of the On-body Injector for Neulasta®

    The On-body Injector for Neulasta® contains batteries, electronics, and a needle. The On-body Injector should be placed in a sharps disposal container, with an appropriate sized opening, regardless of whether or not the needle is exposed. Follow instructions provided by your healthcare provider or by state or local laws. To participate in Amgen’s voluntary disposal program, please call 1-844-MYNEULASTA (1-844-696-3852) or sign up now.

  • Who should I contact if I have additional questions about Neulasta® Onpro®?

    Talk to your doctor for more information on Neulasta®, or call the Amgen Medical Information line at (866) 822-4832.

Talk to your doctor about Neulasta® before starting strong chemo

Ask these questions

Important Safety Information

Who should not take Neulasta®?

Do not take Neulasta® if you have had a serious allergic reaction to Neulasta® (pegfilgrastim) or to NEUPOGEN® (filgrastim).

What should I tell my health care provider before taking Neulasta®? Tell your healthcare provider if you:

  • Have sickle cell trait or sickle cell disease
  • Have had severe skin reactions to acrylic adhesives
  • Are allergic to latex
  • Have problems with your kidneys
  • Have any other medical problems
  • Are pregnant or plan to become pregnant. It is not known if Neulasta® may harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if Neulasta® passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are possible serious side effects of Neulasta®?

  • Spleen Rupture. Your spleen may become enlarged and can rupture while taking Neulasta®. A ruptured spleen can cause death. Call your doctor right away if you have pain in the left upper stomach area or left shoulder tip area. This pain could mean your spleen is enlarged or ruptured.
  • A serious lung problem called Acute Respiratory Distress Syndrome (ARDS). Call your healthcare provider or get emergency medical help right away if you get any of these symptoms of ARDS: fever, shortness of breath, trouble breathing, or a fast rate of breathing.
  • Serious Allergic Reactions. Get emergency medical help right away if you get any of these symptoms of a serious allergic reaction with Neulasta®: shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, sweating, and hives.

If you have an allergic reaction during the delivery of Neulasta®, remove the On-body Injector for Neulasta® by grabbing the edge of the adhesive pad and peeling off the On-body Injector. Get emergency medical help right away.

  • Sickle Cell Crises. Severe sickle cell crises, and sometimes death, can happen in people with sickle cell trait or disease who receive filgrastim, a medicine similar to Neulasta®.
  • Kidney injury (glomerulonephritis). Kidney injury has been seen in patients who received Neulasta®. You should notify your healthcare provider right away if you experience puffiness in your face or ankles, blood in your urine or brown colored urine or you notice you urinate less than usual.
  • Increased white blood cell count (leukocytosis). Your doctor will check your blood during treatment with Neulasta®.
  • Capillary Leak Syndrome. Neulasta® can cause fluid to leak from blood vessels into your body’s tissues. This condition is called "Capillary Leak Syndrome" (CLS). CLS can quickly cause you to have symptoms that may become life-threatening. Get emergency medical help right away if you develop any of the following symptoms:
    • swelling or puffiness and are urinating less often
    • trouble breathing
    • swelling of your stomach area (abdomen) and feeling of fullness
    • dizziness or feeling faint
    • a general feeling of tiredness

The most common side effect of Neulasta® is pain in the bones and in your arms and legs.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Neulasta®. Call your doctor for medical advice about side effects. You may report negative side effects to the FDA at 1-800-FDA-1088.

For more information about Neulasta®, talk with your healthcare provider or pharmacist; go to www.neulasta.com, or call 1-844-696-3852 (1-844-MYNEULASTA).

Please see Neulasta® Patient Information.

Important Safety Information
Who should not take Neulasta®?
Do not take Neulasta® if you have had a serious allergic reaction to Neulasta® (pegfilgrastim) or to NEUPOGEN® (filgrastim).
What should I tell my health care provider before taking Neulasta®? Tell your healthcare provider if you:
• Have sickle cell trait or sickle cell disease

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